Ayola has appeared in television shows including Kaos, The Pact Season 1, Grace, Shetland, No Offence, Midsomer Murders, Black Mirror, Noughts + Crosses, Doctor Who, Silent Witness and EastEnders, a number of Shakespearean theatrical performances and feature films such as Been So Long, Now Is Good, Great Moments in Aviation, The i Inside, Dredd, and Sahara. She appeared as Kyla Tyson in the BBC medical drama Holby City from its eighth to eleventh series.