She was the director of the National Neuroscience Institute.
She is the sister of Lee Hsien Loong and the daughter of Lee Kuan Yew.
1973
Lee received a President's Scholarship in 1973, before studying in the medical faculty of the University of Singapore (now the National University of Singapore), where she graduated top of her class with a Bachelor of Medicine and Bachelor of Surgery degree before specialising in paediatrics.
She began working in the paediatric ward at the Singapore General Hospital (SGH) and received board certification from the American Board of Clinical Neuropsychology.
Lee is the daughter of Lee Kuan Yew and Kwa Geok Choo.
She is the younger sister of Lee Hsien Loong and the older sister of Lee Hsien Yang.
1995
Lee enjoys driving and admitted to speeding on a visit to New Hampshire in 1995; she was pulled over by highway police but was released by the sympathetic officer after discussing the caning of Michael Fay.
2015
In 2015, shortly after the death of her father, Lee published an autobiographical book, A Hakka Woman's Singapore, based on columns that she had previously written.
She has publicly spoken against hero worship of the founding Prime Minister.
2016
In 2016, an editor at The Straits Times accused Lee of plagiarism in an unpublished article.
Lee has publicly supported freedom of speech and stated that she would cease writing for the newspaper following the editorial dispute.
2017
However, they were in a dispute in 2017 with Lee Hsien Loong over their late father's will with regard to the house at 38 Oxley Road.
They "felt threatened by Lee Hsien Loong's misuse of his position and influence over the Singapore government and its agencies to drive his personal agenda".
They alleged that their brother thwarted the will of their father in order to use the house as a monument to milk his father's legacy.
They also criticised the influence of Ho Ching over the government, and alleged that the Prime Minister harboured political ambitions for his son, Li Hongyi.
A special parliamentary session was held to clear the Prime Minister of any wrongdoings and the siblings agreed to keep the dispute private after the session.
2020
In August 2020, Lee stated she had been diagnosed with progressive supranuclear palsy, a rare brain disorder that results in the weakening of certain muscles.
In 2022, Lee reportedly sold a property worth S$50 million to Yonghong Shi, a cofounder of Haidilao.
Lee and her brother, Lee Hsien Yang, are the joint administrators and executors of Lee Kuan Yew's will.