Canfield earned a Bachelor of Arts degree majoring in English and graduated cum laude from Yale College in 2014.
2017
She then attended and graduated from the David Geffen School of Drama at Yale University with an MFA in Acting in 2017.
Her great grandfather, Cass Canfield, was a well-known book publisher.
2018
She is best known for her role as Jess Jordan on the HBO series Succession (2018–2023).
She was also main cast member Beth DeVille on the post-apocalyptic drama Y: The Last Man (2021).
Canfield also plays as a detective, Janine Harris, on the Peacock crime drama series The Calling (2022).
2019
Canfield played the role of Christina in the 2019 revival of Maria Irene Fornes's play Fefu and Her Friends at the Theatre for a New Audience in Brooklyn.
Canfield featured in the recurring role of Kendall Roy's executive assistant, Jess Jordan, in the HBO comedy-drama Succession, first appearing in the show's second episode, and continuing in the role throughout the remainder of the show.
Canfield's role as Jordan was highlighted by The Ringer critic Jessica MacLeish in an article titled 'An Ode to Jess Jordan' during the second season.
In 2021, Canfield starred as Beth DeVille, the girlfriend of lead character Yorick Brown, the only male survivor of a virus that wipes out all others with a Y-chromosome, on the FX comic-book adaptation Y: The Last Man.
In 2022, Canfield portrayed an NYPD detective, Janine Harris, in the crime drama The Calling.