Pinina participated in almost every criminal act ordered by the cartel: the assassinations of Lara and El Espectador director Guillermo Cano Isaza in 1986, the bombing of the El Espectador building in 1989, the assassination of Police Colonel Jaime Ramírez Gómez in 1986, the kidnap and murder of Carlos Mauro Hoyos in 1988, the murder of the Antioquia governor Antonio Roldán Betancur in 1989, the assassination of the Police Colonel Valdemar Franklin Quintero in 1989, cooperation with the arrangement of the DAS Building bombing in 1989 (leaving 52 dead and at least 600 wounded), involvement in the bombing of an Avianca airplane on 27 November 1989 (110 people killed), participation in the killing of many police officers as well as the assassination of the magistrate of Colombian Supreme Court Hernando Baquero Borda in 1986, participation in the assassination of presidential candidate Luis Carlos Galán in 1989 and the war between the Medellin Cartel and the Cali Cartel along with other criminal acts such as car bombings.